Using serotonin and LSD as controls for a radioligand binding experiment for Novel NBOMe psychedelics.3yr ⋅ canmountains ⋅ r/Psychedelics
I work in a psychedelic drug research group our chemical supply company sent us this 😂. Definitely a strange thing to see in a university3yr ⋅ canmountains ⋅ r/CannabisExtracts
High-powered GPUs help a lot with in-silico psychedelic drug modeling especially when they are zip-tied to the glass panel of a PC case sitting on a cardboard box. This is research at its finest.🤣2yr ⋅ canmountains ⋅ r/Biochemistry
Psilocin on the left and LSD on the right have similar amino acid interaction with serotonin 2b receptor. Can anyone think of any other functional groups to replace the carbonyl within the LSD molecule? I want to keep the diethylamine but replace the carbonyl with something else. Any ideas?3yr ⋅ canmountains ⋅ r/OrganicChemistry
The purple, white and red spheres represent CP55,940. When a person smokes or ingests cannabis the binding of THC to this part of the receptor produces intoxication. The blue, pink, white and red spheres represent an experimental compound that binds to the receptor and reduces seizures.4yr ⋅ canmountains ⋅ r/chemistry
Can Anyone Draw out these 2 mechanisms for me. I know the top one is dephosphorylation and the bottom is acid hydrolysis of an ester. I don't know exactly how they work and am looking for help.3yr ⋅ canmountains ⋅ r/OrganicChemistry
The purple, white and red spheres represent CP55,940. When a person smokes or ingests cannabis the binding of THC to this part of the receptor produces intoxication. The blue, pink, white and red spheres represent an experimental compound that binds to the receptor and reduces seizures.4yr ⋅ canmountains ⋅ r/DrugNerds
